Endocrine Abstracts

Introduction: Current guidelines from The Endocrine Society indicate that 2 different tests from urinary free cortisol (UFC) measurement, salivary cortisol (SC) measurement, low-dose dexamethasone suppression test (LDDST) or overnight dexamethasone suppression test (ODST) are required to diagnose Cushing’s syndrome (CS). The low-dose dexamethasone test (LDDST) is often used as the confirmatory test when diagnosing CS. The overnight d...

Introduction: Current guidelines from The Endocrine Society indicate that 2 different tests from urinary free cortisol (UFC) measurement, salivary cortisol (SC) measurement, low-dose dexamethasone suppression test (LDDST) or overnight dexamethasone suppression test (ODST) are required to diagnose Cushing’s syndrome (CS). The low-dose dexamethasone test (LDDST) is often used as the confirmatory test when diagnosing CS. The overnight d...

Introduction: Up to half of patients with carcinoid syndrome develop carcinoid heart disease; this is thought to be mediated by serotonin from disordered tryptophan metabolism. Valve degeneration can lead to right heart failure which drives morbidity and mortality in this patient population. Surgical replacement of affected valves is an effective therapy. Peptide receptor radiotargeted therapy (PRRT) has demonstrated better progression-free survival compared to high dose sando...

Introduction: Gastric NENs are increasingly being diagnosed at endoscopy. The majority of these are type 1 gastric NEN. However, around 10–20% can be type 3 or type 4 Gastric NENs.Methods: A retrospective review performed of 54 patients with gastric NENs referred to a tertiary centre during 2014 to 2019.Results: Of the 54 cases referred, 45 were type 1 gastric NENs and the 9 were type 3 Gastric NENs. Of the 45 type 1 gastric N...